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Animals not in a pasture at the end of a playthrough are carried over to a new game. So around 16Y 3M, remove your space pandas and other best animals so you can use them right away in the next new game. You can put them back in your pasture after high score is calculated.
The Kairo Angel and Kairo Tank are a great combo. The angel will level up your kairobots faster while the tank can hit all three rows for massive damage. I recommend saving a dove wings and firework through the end of the game to be able to research these allies early in the next play through.
Dr. Kairo's virus attack seems to do damage based on a percent of the current target's remaining health. This means it's not very good when fighting a stack of monsters, but is excellent against single big monsters with a lot of hit points.